Our Practical Biomarker Experience

Equipment Platforms:

  • Mesoscale Discovery Sector Imager 600 (2)
  • Luminex Flexmap 3D (2)
  • ProteinSimple ELLA (2)
  • Spectramax 384 (2) – (UV/VIS)
  • Spectramax – L (2) – (Luminescence)
  • Perkin Elmer Envision – (Fluorescence)
  • Hamilton Starlet (2)

De novo Assays

  • Target Engagement
  • Mechanistic
  • Pharmacodynamic
  • Disease Specific
  • Ex-vivo Stimulation

Individual Analytes

*Updated regularly

anti-KLH IgG
anti-KLH IgM
CCL-24/Eotaxin-2
CXCL13
Eotaxin 1/CCL11
Eotaxin-3/CCL26
GM-CSF/CSF2
IFN-γ
IL-10/CSIF
IL-12/IL-23p40
IL-12p70
IL-13
IL-15
IL-16/LCF
IL-17a

IL-1a
IL-1β / leukocytic pyrogen
IL-2/TCGF
IL-2Ra/CD25
IL-4
IL-5
IL-6
IL-7
IL-8 (HA)
IL-8
IP-10
MCP-1
MCP-4/CCL13
M-CSF/CSF1
MDC/CCL22

MIP-1α
MIP-1β Neurogranin
NF-H
sCD40
sCD40-Ligand
sCD73/5NT
NF-L Ultrasensitive
Placental Growth Factor (PlGF)/PGF
TARC/CCL17
TNF-b
TNF-α
Transthyretin (TTR) VEGF

* Experience with many additional biomarker assays

Biomarker Experience

Multiplex Panels*

  • V-Plex Chemokine Panel 1
  • V-Plex Cytokine Panel 1
  • V-Plex Pro-Inflammatory Panel 1
  • V-Plex Th17 Panel
  • V-Plex Abeta Peptide Panel 1
  • V-Plex Neuroinflammation Panel 1
  • V-Plex Angiogenesis Panel
  • V-Plex Vascular Injury Panel
  • V-Plex NHP Cytokine Panel
  • Multiple Luminex Panels – please enquire
  • Multiplex and Multianalyte ELLA Panels

* Experience with many additional biomarker assays

Diseases/Therapeutic Areas

Allergy
Anemia
Bone Metabolism
Cardiovascular
Diabetes
Growth
Inflammation Immunology
Metabolic
Endocrinology
Apoptosis
Neuroscience
Oncology
COPD

Matrices

Serum
Plasma
Whole Blood
CSF
Urine
Saliva
Sputum
Broncheolar Lavage Fluid
Nasal Aspirate
Tears
Tissue lysates
Synovial Fluid
Vitreous Humor Aqueous Humor
Semen
Sweat
Blister Fluid