Publication in The AAPS Journal

By Kayla J. Spivey | January 13, 2026

Industry best practices don’t write themselves.

Immunologix Laboratories team members John Allinson, Dr. Robert Neely, and Dr. Lauren Stevenson co-authored a new AAPS Journal publication: “Best practices in the application of parallelism for biomarker assay validation.”

The paper tackles a persistent challenge in bioanalytical method development: while parallelism is recognized as critical for confirming analyte recognition and surrogate matrix suitability, detailed practical guidance has been limited and often confused with dilution linearity or spike recovery experiments.

Key contributions include:
→ Structured approach to parallelism experiment design and execution
→ Statistical and graphical interpretation frameworks
→ Guidance for continuous evaluation throughout the assay lifecycle
→ Case studies demonstrating real-world application

Read the full paper: https://link.springer.com/article/10.1208/s12248-025-01176-w

King, L., Allinson, J., Amaravadi, L., Kernstock, R., Garofolo, F., Gunsior, M., Jones, B., Mathews, J., Neely, R., Nelson, R., Pepin, M.-O., Shen, H., Stevenson, L., & Voelker, T. (2026). Best practices in the application of parallelism for biomarker assay validation. AAPS Journal, 28, Article 50.